公司
Pamplona Therapeutics is an early-stage drug discovery company developing targeted protein degradation (TPD) therapy to address unmet needs in autoimmune and oncology diseases. The company has built a cutting-edge, AI-driven TPD drug discovery platform (ASTRIDE®) that integrates target structure prediction, high-throughput virtual screening, molecular docking, molecule generation, and ubiquitination assessment modules. Harnessing this AI-driven platform, Pamplona advanced its first autoimmune-focused preclinical candidate within 18 months of its inception, and its first IND was cleared by the FDA at the end of 2025. With this proven and highly scalable AI-based platform, we aim to tackle additional undruggable targets and address a broad range of global disease challenges.
簡介
AI Meets Protein Degradation: Redefining Medicine