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Our mission is to revolutionise drug and therapeutic discovery & development, and provide a novel and affordable solution for medical treatment, patient stratification and disease diagnostics for rare diseases of newborns.
We observed that there is a lack of effective treatment for rare diseases of newborns and there is an urgent need of human organ proxies in the dish for disease modelling, and biomarker, drug and therapeutic discovery.
To fill the gap, we will provide state-of-the-art and first-in-class human disease organoids for personalised precision medicine, regenerative medicine and preventive medicine for rare diseases of newborns. Our organoid platform marks the beginning of the deployment of a novel and affordable solution for medical treatment, patient stratification and disease diagnostics. Our platform will have a significant impact in reducing mortality rate, saving billions of dollars in healthcare costs and improving the quality of life of individuals.
Our human IPSC-derived organoids is an immediate solution to the problem.
An organoid is a miniaturised and simplified version of an organ produced in vitro in 3-dimensions that shows realistic micro-anatomy, resembling a near-to-native mini-organ in the dish. They are derived from tissue stem cells, embryonic stem cells or induced pluripotent stem cells (IPSCs), which can self-organise in 3-dimensional culture owing to their self-renewal and differentiation capacities. Organoids are used by scientists to study diseases and treatments in a laboratory.
GLOAS provides state-of-the-art technology platforms including patients’/normal human induced pluripotent stem cells (hIPSCs); first-generation patient’s/normal hIPSC-derived human organoids with one cell type (human organoids 1.0); second-generation advanced patient’s/normal human organoids with multiple cell types (human organoids 2.0); tissue hydrogel; and fabricated human bile duct to revolutionise the discovery and development of drugs and therapeutics for neonatal rare diseases.